🔎 Understanding Neurogenic Pain: Beyond Tissue, It’s the Language of the Nervous System

Neurogenic pain is not just a symptom; it reflects dysfunction within the nervous system, not merely structural damage. Unlike nociceptive pain, which is triggered by external stimuli, neurogenic pain can persist even in the absence of ongoing injury, due to persistent alterations in how the nervous system interprets and integrates signals.

This type of pain is common in conditions such as peripheral neuropathy, radiculopathy, neuralgias, postsurgical pain, dysesthesias, and complex regional pain syndromes. Clinically, it manifests as burning, electric shocks, stabbing sensations, numbness, hypersensitivity, hyperalgesia, or allodynia. But beyond these symptoms, neurogenic pain represents a profound dysfunction in the person’s neurobiology.

At its root lies chronic neuroinflammation, loss of central modulation, peripheral sensitization, and axonal conduction dysfunction. To address it effectively, therapy must go beyond symptom management and aim to reset the nervous system at a functional and regenerative level.

💉 PIT – Perineural Injection Therapy: Restoring Health to the Neural Environment

Perineural Injection Therapy (PIT) is a revolutionary tool in regenerative functional medicine. Through microinjections around superficial sensory nerves, PIT directly targets receptors involved in neurogenic inflammation—particularly TRPV1, ASIC, and P2X receptors.

These receptors become activated by tissue damage, metabolic toxins, ischemia, or oxidative stress. PIT utilizes safe, non-toxic solutions—like diluted dextrose—to reduce nerve terminal irritability and normalize perineural signaling.

🎯 Common indications:

• Persistent postsurgical pain
• Nerve entrapment syndromes
• Inflammatory peripheral neuropathy
• Chronic limb pain
• Atypical facial pain

The clinical protocol involves identifying key points of nerve sensitivity—guided anatomically or by ultrasound—and injecting the solution around the affected nerve pathways. As signaling normalizes, symptoms progressively subside, allowing patients to regain function without chronic medication or invasive blocks.

⚡ EMTT – Electromagnetic Transduction Therapy: High-Frequency Biophysics for Neural Recovery

Electromagnetic Transduction Therapy (EMTT) represents the next evolution in electromagnetic therapy. Through high-frequency (up to 100 kHz), high-intensity (up to 120 kT/s) pulsed fields, EMTT deeply penetrates neuromuscular and osseous tissues without heating or superficial irritation.

Neurologically, EMTT enhances neural membrane repolarization, promotes mitochondrial recovery, and supports synaptic normalization. It also improves lymphatic drainage and reduces interstitial inflammation, which is critical in cases like:

• Fibromyalgia
• Chronic neuralgias
• Motor radiculopathies
• Centralized post-viral pain (e.g., post-COVID)
• Central sensitization syndromes

🧲 The procedure is entirely non-invasive: a coil is positioned over the treatment area to deliver controlled electromagnetic impulses. Sessions are short, painless, and well tolerated—even by hypersensitive patients.

🌿 TECAR Therapy: Cellular Activation in Nerves and Soft Tissues

TECAR (Capacitive and Resistive Electric Transfer) is a form of therapeutic radiofrequency that mobilizes ions, boosts cell metabolism, and promotes regeneration in deep tissues.

In the context of neurogenic pain, TECAR contributes by:

• Enhancing perineural oxygenation
• Reducing myofascial stiffness around nerves
• Improving circulation in hypoperfused regions
• Accelerating the removal of neuroinflammatory waste

When combined with PIT or EMTT, TECAR offers synergistic restoration of tissue integrity—especially valuable in chronic neural conditions.

💥 Shock Wave Therapy: A Wave of Energy to Disrupt the Pain Cycle

Shock Wave Therapy has shown clear benefits in chronic pain management, including neurogenic conditions. This technique creates controlled microtraumas that stimulate healing, enhance angiogenesis, and modulate nociceptive transmission.

In cases of entrapped or fibrotic nerves, shock waves can:

• Decompress the neural pathway
• Reactivate axonal conduction
• Downregulate local inflammatory mediators

Properly dosed, shock wave therapy is safe and effective—even in delicate areas like the neck, jaw, scapular region, or pelvis.

🦵 HA Injections: Joint Viscosupplementation with Neurological Impact

Hyaluronic Acid (HA) Injections do more than improve biomechanics in degenerative joints. By reducing chronic nociceptive input from deteriorated joints, they decrease the afferent load to the central nervous system, helping prevent sensitization.

For example, in osteoarthritic knees that cause referred pain to the thigh or hip, HA can interrupt that pain feedback loop and support neurological reorganization.

🧘 Physical and Occupational Therapy: Neuroplasticity Through Movement

Functional rehabilitation is essential to consolidate progress achieved with PIT, EMTT, and HA. Physical Therapy retrains the nervous system to respond with safe and efficient motor patterns, while Occupational Therapy helps patients adapt daily activities without triggering pain responses.

These disciplines promote positive neuroplasticity, reversing dysfunctional patterns ingrained by chronic pain.

🧠 Key techniques for neurogenic pain:

• Progressive proprioceptive retraining
• Sensory desensitization therapy
• Mirror therapy and cortical retraining
• Segmental stabilization and motor control exercises

🗣️ TMJ and Craniofacial Neurogenic Pain: The Forgotten Axis

The temporomandibular joint (TMJ) is often overlooked in neurogenic pain analysis. Dysfunction in this joint may irritate the trigeminal nerve, triggering headaches, vertigo, tinnitus, facial pain, and upper cervical discomfort.

📍 A proper approach should involve:

• PIT to myofascial trigger points in the masseter, temporalis, and pterygoid muscles
• EMTT or TECAR applied to the cervicocranial junction
• Mandibular rehabilitation through guided physical therapy

By reducing nociceptive input from the TMJ, the sensory overload on the trigeminal system decreases, improving complex cranio-cervical symptoms.

🔁 Multimodal Strategy: Neuroregeneration, Rehabilitation, and Function

Treating neurogenic pain requires a multimodal strategy combining:

• Neurochemical modulation (PIT)
• Deep biophysical stimulation (EMTT, TECAR)
• Joint and neural regeneration (HA, PRP, Shock Wave)
• Neuroeducation and functional retraining (PT/OT)

This approach allows us to reset the nervous system, break the pain memory cycle, and restore function—without relying on chronic pharmacotherapy or invasive procedures.